Respiratory Alkalosis

CO2 + H2O H2CO3 H+ + HCO3

In respiratory alkalosis there is low pCO2 and a consequent high pH as a result of the equation moving to the left and lowering H+. pCO2 has been lowered by either hyperventilation or drug-induced stimulation of breathing. [2,3]

Respiratory alkalosis is often associated with processes that cause hyperventilation differentials can be remembered with CHAMPS. [8]

CHAMPS [8]

  • CNS disease (stroke, haemorrhage, psychogenic)
  • Hypoxia (pneumonia, PE, asthma, altitude)
  • Anxiety, pain
  • Mechanical or excessive ventilation
  • Progesterone, pregnancy
  • Salicylates and sepsis