Acute Rhabdomyolysis Case 3
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Question 1 of 3
1. Question
A patient has been trapped under a tube train below his waist for 90 minutes until he was freed.
He has arrived hypotensive and is being resuscitated.
His CK is grossly elevated and you presume he has a crush syndrome and consequent rhabdomyolysis.
This patient has crush syndrome. Which of the features of crush syndrome is usually the first to manifest?
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Question 2 of 3
2. Question
How long can muscle be hypoxic before damage becomes permanent?
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Question 3 of 3
3. Question
What are the pathophysiological causes of the five serious clinical sequelae of rhabdomyolysis?
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- Hypovolaemia
- Hyperkalaemia
- Metabolic acidosis
- Acute renal failure
- DIC
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Sequestration of fluid within muscle and myocytes
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Release of potassium into the systemic circulation
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Release of organic acids, phosphate and sulphate
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Nephrotoxic effects release of myoglobin, inflammatory mediators
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Consumption of clotting factors
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