Local anaesthetics – pharmacology question
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1. Question
Esters and amides have distinct characteristics. See if you can identify the characteristics of each.
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- Of the two this is the more unstable, Metabolism is mainly by plasma cholinesterases, Cocaine is a member of this group
- Unaffected by autoclave procedures, Lidocaine is a member of this group, Metabolism is mainly through the liver, Of the two this causes fewer hypersensitivity reactions
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Ester
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Amide
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