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Typically, patients present with a history of weakness and fatigue of voluntary (skeletal) muscles. Symptoms worsen on exertion and improve at rest. There is diurnal variation with worsening of symptoms in the later part of the day.
Which are the most commonly affected muscles in order of frequency?
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Muscles of facial expression (facial weakness)
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Levator palpebrae superioris (ptosis)
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Extraocular muscles (diplopia)
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Proximal limb muscles
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Neck flexors/extensors
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