Seizure Prophylaxis & treatment

Post-traumatic seizures affect around 15% of those experiencing a blunt severe traumatic brain injury. The role of routine seizure prophylaxis following traumatic brain injury is controversial, though clinical or EEG evidence of post-traumatic seizures is an established indication for anti-epileptic drugs and guidelines suggest commencing AEDs where the benefits are felt to outweigh the risks of treatment2. There is an increasing trend favouring Levetiracetam over Phenytoin for seizure prophylaxis and treatment22.