The NEXUS Chest decision instrument has been validated to identify which patients require chest imaging following blunt trauma in patients over the age of 14. The rule states that a patient:
does not need a routine chest x-ray.5
This has been validated by the author of the rule in a multicentre study at nine level 1 Trauma centres in the US which enrolled 9905 patients. Thoracic injury seen on chest imaging was seen in 1478 (14.9%) patients, with 363 (24.6%) of these having major clinical significance. 1079 (73.0%) had minor clinical significance, and 36 (2.4%) had no clinical significance.
The NEXUS Chest rule had a sensitivity of 98.8% (95% CI, 98.1%99.3%), a negative predictive value of 98.5% (95% CI, 97.6%.699.1%), and a specificity of 13.3% (95% CI, 12.6%14.1%) for thoracic injury. The sensitivity and negative predictive value for thoracic injury with clinically major injury were 99.7% (95% CI, 98.2%100.0%) and 99.9% (95% CI, 99.4%100.0%), respectively. There has been no external validation study in the UK.6