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CNS infections are relatively rare, but form a very important differential diagnosis in the unwell patient presenting to the ED.
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Cystic Fibrosis is caused by a mutation in a gene that encodes cystic fibrosis transmembrane conductance regulator (CFTR) protein, which is expressed in many epithelial and blood cells.
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Lyme disease is a spirochete infection transmitted by ticks. ED presentation, although rare, is important to identify to enable early treatment.