Authors: Joseph Walsh, Emma Formoy-Walsh / Editors: Frances Balmer / Codes: / Published: 14/07/2025
This module covers the management of Nausea and Vomiting of Pregnancy (NVP), across the spectrum from mild symptoms to Hyperemesis Gravidarum (HG).
Learning objectives
After completing this session, you will be able to:
- Assess a patient who attends with nausea and vomiting in pregnancy
- Stratify the severity of symptoms in patients with nausea and vomiting in pregnancy
- Understand the treatment options to manage nausea and vomiting in pregnancy
References
- Gadsby R, Rawson V, Dziadulewicz E, Rousseau B, Collings H. Nausea and vomiting of pregnancy and resource implications: the NVP Impact Study. Br J Gen Pract. 2019 Mar;69(680):e217-e223.
- Nelson-Piercy C, Dean C, Shehmar M, et al. The Management of Nausea and Vomiting in Pregnancy and Hyperemesis Gravidarum (Green-top Guideline No. 69). BJOG. 2024 Jun;131(7):e1-e30.
- Fiaschi L, Nelson-Piercy C, et al. Clinical management of nausea and vomiting in pregnancy and hyperemesis gravidarum across primary and secondary care: a population-based study. BJOG. 2019 Sep;126(10):1201-1211.
- Mitchell-Jones N, Gallos I, et al. Psychological morbidity associated with hyperemesis gravidarum: a systematic review and meta-analysis. BJOG. 2017 Jan;124(1):20-30.
- Fiaschi L, Nelson-Piercy C, et al. Adverse Maternal and Birth Outcomes in Women Admitted to Hospital for Hyperemesis Gravidarum: a Population-Based Cohort Study. Paediatr Perinat Epidemiol. 2018 Jan;32(1):40-51.
- Fejzo M, Rocha N, Cimino I, et al. GDF15 linked to maternal risk of nausea and vomiting during pregnancy. Nature. 2024 Jan;625(7996):760-767.
- Irish Medicines in Pregnancy Service: Position Statement on Ondansetron Use in Pregnancy. 23 October 2019.
- Nana M, Tydeman F, Bevan G, et al. Hyperemesis gravidarum is associated with increased rates of termination of pregnancy and suicidal ideation: results from a survey completed by >5000 participants. Am J Obstet Gynecol. 2021 Jun;224(6):629-631.
