Critical Appraisal: Appraising a Treatment, Early Goal Directed Therapy


This session covers the critical appraisal of an important randomised controlled trial.

Learning Objectives

After completing this session you will be able to:

  • Compare pragmatic and explanatory
  • Define effectiveness and efficacy
  • Define surrogate outcomes
  • Define absolute and relative risk reduction
  • Define number needed to treat
  • Define bias and confounding


CASP International Network

Refer to the following text for additional information:

Greenhalgh T. How to Read a Paper. BMJ Publishing Group, 2001.

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