July Virtual Journal Club – A practical risk score for early prediction of neurological outcome after out-of-hospital cardiac arrest: MIRACLE2

Author: Rajesh Chatha / Editor: Rajesh Chatha, Robert Hirst / Codes: / Published: 22/07/2021

At TERN Education we are keen to help you all learn how to critically evaluate the evidence behind your practice. In order to do this, we are producing monthly virtual journal club modules on RCEMLearning. These give you the opportunity to critically consider your practice and earn a certificate which demonstrates the new curricular requirement to be engaged in critical appraisal activity. When you finish, click the link to the forum to discuss this months paper with colleagues around the country.

Interested in writing a module? We are looking to recruit regional teams to write future modules. Email us at tern.education@rcem.ac.uk.

START

References

  1. Semeraro F, Greif R, Bttiger B, Burkart R, Cimpoesu D, Georgiou M et al. European Resuscitation Council Guidelines 2021: Systems saving lives. Resuscitation 2021; 161: 80-97. doi:10.1016/j.resuscitation.2021.02.008
  2. Nikolaou, N, Dainty K, Couper K, Morley P, Tijssen J, Vaillancourt C et al. A systematic review and meta-analysis of the effect of dispatcher-assisted CPR on outcomes from sudden cardiac arrest in adults and children. Resuscitation 2019; 138: 82-105. doi:10.1016/j.resuscitation.2019.02.035
  3. Benger J, Kirby K, Black S, Brett S, Clout M, Lazaroo M et al. Effect of a Strategy of a Supraglottic Airway Device vs Tracheal Intubation During Out-of-Hospital Cardiac Arrest on Functional Outcome: The AIRWAYS-2 Randomized Clinical Trial. JAMA 2018; 320(8):: 779-791. doi:10.1001/jama.2018.11597
  4. Nichol, G, Sayre, M, Guerra F, Poole J. Defibrillation for Ventricular Fibrillation: A Shocking Update. Journal of the American College of Cardiology 2017; 70(12): 1496-1509. doi:10.1016/j.jacc.2017.07.778
  5. Pollack, R, Brown S, Rea T, Aufderheide T, Barbic D, Buick J et al. Impact of Bystander Automated External Defibrillator Use on Survival and Functional Outcomes in Shockable Observed Public Cardiac Arrests. Circulation 2018; 137(20): 2104-2113. doi:10.1161/CIRCULATIONAHA.117.030700
  6. Resuscitation Council UK. 2021 Resuscitation Guidelines. [accessed 5 July 2021]
  7. Ong M, Pellis T, Link M. The use of antiarrhythmic drugs for adult cardiac arrest: a systematic review. Resuscitation 2011; vol. 82(6): 665-70. doi:10.1016/j.resuscitation.2011.02.033
  8. Khan S, Winnicka L, Saleem M, Rahman H, Rehman N. Amiodarone, lidocaine, magnesium or placebo in shock refractory ventricular arrhythmia: A Bayesian network meta-analysis. Heart & Lung : The Journal of Critical Care 2017; 46(6): 417-424. doi:10.1016/j.hrtlng.2017.09.001
  9. Miraglia D, Miguel L, Alonso W et al. Esmolol in the management of pre-hospital refractory ventricular fibrillation: A systematic review and meta-analysis. American Journal of Emergency Medicine 2020; 38(9): 1921-1934. doi:10.1016/j.ajem.2020.05.083
  10. Cheskes S, Dorian P, Feldman M, McLeod S, Scales D, Pinto R et al. Double sequential external defibrillation for refractory ventricular fibrillation: The DOSE VF pilot randomized controlled trial. Resuscitation 2020; 150: 178-184. doi:10.1016/j.resuscitation.2020.02.010
  11. Haywood K, Ji C, Quinn T, Nolan J, Deakin C, Scomparin C et al. Long term outcomes of participants in the PARAMEDIC2 randomised trial of adrenaline in out-of-hospital cardiac arrest. Resuscitation 2021; 160: 84-93. doi:10.1016/j.resuscitation.2021.01.019
  12. Perkins G, Ji C, Deakin C, Quinn T, Nolan J, Scomparin C, et al. A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest. New England Journal of Medicine 2018; 379(8): 711-721. doi:10.1056/NEJMoa1806842
  13. Perkins G, Ji C, Achana F, Black J, Charlton K, Crawford J et al. Adrenaline to improve survival in out-of-hospital cardiac arrest: the PARAMEDIC2 RCT. Health Technology Assessment 2021; 25.25: 1-166. doi:10.3310/hta25250
  14. Holmberg M, Geri G, Wiberg S, Guerguerian A, Donnino M, Nolan J et al. Extracorporeal cardiopulmonary resuscitation for cardiac arrest: A systematic review. Resuscitation 2018; 131: 91-100. doi:10.1016/j.resuscitation.2018.07.029
  15. Yannopoulos D, Bartos J, Raveendran G, Walser E, Connett J, Murray T et al. Advanced reperfusion strategies for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation (ARREST): a phase 2, single centre, open-label, randomised controlled trial. Lancet 2020; 396(10265): 1807-1816.
  16. Ebell M, Jang W, Shen Y, Geocadin R et al. Development and validation of the Good Outcome Following Attempted Resuscitation (GO-FAR) score to predict neurologically intact survival after in-hospital cardiopulmonary resuscitation. JAMA Internal Medicine 2013; 173(20): 1872-8. doi:10.1001/jamainternmed.2013.10037.
  17. Pareek N, Kordis P, Beckley-Holescher N, Pimenta D, Kocjancic S, Jazbec A et al. A practical risk score for early prediction of neurological outcome after out-of-hospital cardiac arrest: MIRACLE2. European Heart Journal 2020; 41(47): 4508-4517. doi:10.1093/eurheartj/ehaa570
  18. Sedgwick P. Logistic regression. BMJ 2013; 347: f4488. doi:10.1136/bmj.f4488
  19. Hidalgo B, Goodman, M. Multivariate or multivariable regression?. American Journal of Public Health 2013; 103(1): 39-40. doi:10.2105/AJPH.2012.300897
  20. Kalan M, Jebai R,Zarafshan E, Bursac Z. Distinction Between Two Statistical Terms: Multivariable and Multivariate Logistic Regression. Nicotine & Tobacco Research 2020:ntaa055. doi.org/10.1093/ntr/ntaa055
  21. Goodacre S. Critical appraisal for emergency medicine: 5 Evaluation of a diagnostic test. Emergency Medicine Journal. 2009; 26(1): 53-6. doi:10.1136/emj.2007.057349
  22. Deeks J, Altman D. Diagnostic tests 4: likelihood ratios. BMJ 2004; 329: 168 doi:10.1136/bmj.329.7458.168
  23. Mandrekar J. Receiver Operating Characteristic Curve in Diagnostic Test Assessment. Journal of Thoracic Oncology 2010; 5(9): 1315-1316. doi:10.1097/JTO.0b013e3181ec173d.

Module Content

Expand All

Leave a Reply

BACK TO POST