Authors: Nigel Harrison, Peter Driscoll, Carl Gwinnutt / Editors: Jason Kendall / Reviewer: Nick Blundell, Phil Delbridge / Codes: A2, R1 / Published: 11/08/2022
This session will review the transfer of oxygen from the atmosphere to the body’s tissues.
After completing this session you will be able to:
- Define the important gas laws that govern the carriage of necessary gases from the atmosphere to the pulmonary capillaries and beyond
- Explain the transport of oxygen in blood and implications of hypoxia and hypoxaemia
- Describe the effects of various physiological factors on the binding of oxygen to haemoglobin as related to the oxygen-haemoglobin dissociation curve
- Recognise the value of therapies in relieving hypoxia and hypoxaemia
- Explain the pulmonary influences on acid-base homeostasis and processes that destabilise the normal equilibrium in clinical disease
References
- Arthur C, Hall JE. Textbook of Medical Physiology. Philadelphia: W.B. Saunders Company, 2000.
- Driscoll P, Brown T, Gwinnutt C et al. A Simple Guide To Blood Gas Analysis. London: BMJ Publishing Group, 1997.
- Lamb JF, Ingram CG, Johnston IA. Essentials Of Physiology. 3rd edn. Oxford: Blackwell Science, 1991.
- Ward JP, Clarke RJ. Physiology At A Glance. Oxford: Wiley Blackwell, 2005.
- West JB. Respiratory Physiology, The Essentials. 9th edn. Baltimore. Lippincott Williams and Wilkins, 2004.
- Roberts F. Respiratory Physiology. In: Wilson I, (ed.) Update In Anaesthesia. Publications Committee WFSA, 2000;12:11, UK.
- Cruickshank S, Hirschauer N. The alveolar gas equation. Continuing Education in Anaesthesia Critical Care & Pain. Vol 4, Issue 1, 2004; 24-27.
- Laws of gas transport. Hyperphysics.
Additional Resources
