Phaeochromocytoma

Author: Rob Stafford / Editor:Tajek B Hassan / Reviewer: Emma Everitt, Rob Stafford / Codes: A1, O7 / Published: 13/09/2021

Description:

Describing the key features relevant to the history of phaeochromocytoma

After completing this session you will be able to:

• Describe the key features relevant to the history of phaeochromocytoma
• Describe the pathophysiological mechanism by which phaeochromocytoma causes its clinical features
• Understand that phaeochromocytoma can mimic common emergency department presentations
• Outline the generic aspects of the management of phaeochromocytoma

References:

1. Platts JK, Drew PJ, Harvey JN. Death from phaeochromocytoma: lessons from a post-mortem survey. J R Coll Physicians Lond. 1995 Jul-Aug;29(4):299-306.
2. Anderson GH Jr, Blakeman N, Streeten DH. The effect of age on prevalence of secondary forms of hypertension in 4429 consecutively referred patients. J Hypertens. 1994 May;12(5):609-615.
3. Whalen RK, Althausen AF, Daniels GH. Extra-adrenal pheochromocytoma. J Urol. 1992 Jan;147(1):1-10.
4.  Pacak K, Linehan WM, Eisenhofer G et al. Recent advances in genetics, diagnosis, localization, and treatment of pheochromocytoma. Ann Intern Med. 2001 Feb 20;134(4):315-329.
5. Neumann HP, Berger DP, Sigmund G et al. Pheochromocytomas, multiple endocrine neoplasia type 2, and von Hippel-Lindau disease. N Engl J Med. 1993 Nov 18;329(21):1531-8. Erratum in: N Engl J Med 1994 Dec 1;331(22):1535.
6. Ramrakha P, Moore K.  Oxford Handbook of Acute Medicine, Oxford,  2004.

Resources:

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• Zendron L, Fehrenbach J, Taverna C et al.  Pitfalls in the diagnosis of phaeochromocytoma. BMJ Mar 2004; 328: 629- 630.
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• Cook RF, Katritsis D. Hypertensive crisis precipitated by a monoamine oxidase inhibitor in a patient with phaeochromocytoma. BMJ. 1990 Mar 3;300(6724):614.
• Rosas AL, Kasperlik-Zaluska AA, Papierska L et al. Pheochromocytoma crisis induced by glucocorticoids: a report of four cases and review of the literature. Eur J Endocrinol. 2008 Mar;158(3):423-429.
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• Wu HW, Liou WP, Chou CC et al. Pheochromocytoma presented as intestinal pseudo-obstruction and hyperamylasemia. Am J Emerg Med. 2008 Oct;26(8):971.
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• De Wilde D, Velkeniers B, Huyghens L et al. The paradox of hypotension and pheochromocytoma: a case report. Eur J Emerg Med. 2004 Aug;11(4):237-239.
• Preuss J, Woenckhaus C, Schwesinger G et al. Non-diagnosed pheochromocytoma as a cause of sudden death in a 49-year-old man: a case report with medico-legal implications. Forensic Sci Int. 2006 Jan 27;156(2-3):223-228.
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• Blake MA, Pheochromocytoma. Medscape, 2021.